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. 2019 Sep 24;9:946. doi: 10.3389/fonc.2019.00946

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Copyright © 2019 He, Zeng, Luo, Liu, Zhang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Typical imaging manifestations of patients with local recurrence treated with extended curettage. (a) Anteroposterior and lateral radiographs showed that the proximal and lateral parts of the right tibia had obvious osteolytic foci at the original site. (b) Computed tomography (CT) scan confirmed low-density osteolytic changes in the original site. (c) Extended curettage, cement filling, and subchondral bone grafting were performed after relapse of GCTB was confirmed by biopsy (white arrow points to the lesion).