Wnt1 |
Activates EMT and promotes metastasis in breast cancer |
(159) |
|
M2 (IL4) macrophages act as a source of Wnt1 and promote Wnt signaling in intestinal crypts in IBD |
(51) |
|
Hypoxic macrophages impair autophagy in epithelial cells through Wnt1 |
(131) |
Wnt2b |
M2 (IL4) macrophages overexpress Wnt2b in a STAT6-dependent manner and accelerate intestinal wound healing in mice |
(52) |
|
M2 (CD45+CD64+CD206+CD16+) macrophages act as a source of Wnt2b and promote EMT in CD |
(148) |
Wnt3a |
M2 (IL4) macrophages act as source of Wnt3a |
(51) |
|
Inhibits proinflammatory cytokine secretion of murine macrophages |
(134) |
|
Drives parenquimal regeneration of hepatocytes |
(168) |
Wnt4 |
Restores proliferative defects in post-injury lung epithelial cells produced by TFF2-deficient macrophages |
(138) |
Wnt5a |
Enhances the invasiveness of cancer cells in breast cancer |
(124) |
|
Regulates inflammatory cytokine secretion, polarization, and apoptosis in mycobacterium tuberculosis-infected macrophages |
(137) |
|
Promotes kidney fibrosis by stimulating Yap/Taz-mediated macrophage M2 polarization |
(150) |
Wnt5b |
Induces tumor progression of breast cancer |
(157) |
Wnt6 |
Up-regulated in the colonic mucosa and in CD16+ macrophages of STAT6 knockout mice in an IBD model |
(147) |
|
Drives macrophage polarization toward the M2 phenotype |
(135) |
Wnt7a |
M2 (IL4) macrophages act as a source of Wnt7a and promote lung fibrosis |
(149) |
Wnt7b |
Induces tumor progression of breast cancer |
(157) |
|
Promotes cholangiocarcinoma growth |
(158) |
|
M2 (IL4) macrophages overexpress Wnt7b in a STAT6-dependent manner and accelerate intestinal wound healing in mice |
(52) |
|
Wound-healing macrophages promote tubular epithelial cell proliferation, angiogenesis and kidney repair |
(127) |
|
Affects blood vessel formation |
(143, 144) |
Wnt10b |
M2 (IL4) macrophages overexpress Wnt10b in a STAT6-dependent manner and accelerate intestinal wound healing in mice |
(52) |
Wnt16 |
Restores the proliferative defect in lung epithelial cells post-injury produced by TFF2-deficient macrophages |
(138) |