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| Study | Reason for exclusion |
|---|---|
| Gramer 2009 | Not an RCT. |
| Gropmann 2011 | Trial was terminated prematurely due to poor recruitment. |
| Nwose 2008 | Participants and outcome measures are not relevant to the review. |
| Utz 2012 | Outcomes not relevant to the review. A pharmacogenetic test of responsiveness to sapropterin dihydrochloride. |
RCT: randomized controlled trial
