Jorgenson 2000.
Methods | Study conducted in Denmark (presumed single centre) | |
Participants | 120 healthy term parturients consenting to spinal anaesthesia for elective caesarean section; patients with pre‐eclampsia, arterial hypertension or multiple pregnancy were excluded | |
Interventions | Warmed saline heated to 37°C (n = 57) Cold saline at 21°C (n = 56) Each participant was infused with 20 mL/kg 15 minutes before spinal, then 10 mL/kg in the 20 minutes after spinal injection |
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Outcomes | Decrease in core temperature (location measured not specified); discomfort; incidence of shivering; blood pressure; heart rate | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Randomization was achieved with computer‐generated codes |
Allocation concealment (selection bias) | Low risk | Codes were placed in sealed envelopes, which were opened after the participant arrived to the theatre |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not described |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | 7 participants were withdrawn from the study: 1 because of violation of selection criteria, 2 because of failed spinal anaesthesia and 5 because of protocol violations |
Selective reporting (reporting bias) | Low risk | No evidence of this |
Other bias | Low risk | None |