Woolnough 2009.
Methods | Single‐centre study from UK | |
Participants | 75 female patients undergoing elective caesarean section for a singleton pregnancy greater than 37 weeks of gestation under combined spinal‐epidural anaesthesia Exclusion criteria: pyrexia, pre‐eclampsia, drug therapy other than antacids or vitamins, patients at increased risk of intraoperative bleeding |
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Interventions | Group 1 (n = 25) room temperature intravenous fluids: 2.0 ± 0.4 litres infused Group 2 (n = 25) prewarmed intravenous fluids: 2.1 ± 0.4 litres infused Group 3 (n = 23) in‐line warming: 2.4 ± 1.4 litres infused |
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Outcomes | Tympanic temperature measured every 15 minutes; blood loss; shivering; subjective feelings of hot or cold Shivering assessed using a 3‐point scale: 0 = no shivering; 1 = mild, intermittent shivering; 2 = intense, continuous shivering |
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Notes | Both groups of warmed fluids combined for analysis | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | 'Computer generated random numbers and sealed envelopes' |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | To maintain blinding, all groups had fluids delivered via a hotline fluid warmer, which was switched on only for group 3. The investigator was not allowed to touch any fluid bags or to give any IV drugs |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | A blinded investigator recorded temperature and assessed the degree of shivering |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up |
Selective reporting (reporting bias) | Low risk | No evidence of this |
Other bias | Low risk | None |