Eick 2011.
Methods | Controlled before‐after study | |
Participants | Children (n = 46), mean age 6.6 years. The homes where at least 1 asthmatic child under 12 years lived permanently and which received income‐related, state‐funded benefits were included and the control homes were randomly chosen from these | |
Interventions | Retrofitted, whole‐house mechanical ventilation with heat recovery system, laminate flooring, anti‐allergy bed clothes, a central vacuum cleaner and central heating were installed | |
Outcomes | Buildings, temperature, relative humidity, fine particles, coarse particles, wall/wall surface moisture, dust mite allergen, microbial colonies, carbon dioxide, carbon monoxide Participants: asthma‐related and other respiratory symptoms |
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Notes | Mould or mould damage was observed in 55% of the homes before intervention. Only the pilot study was included in the review | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Not blinded |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Not blinded |
Unplanned subgroup analyses (16) | Low risk | No data dredging |
Follow‐up (17) | Low risk | Follow‐up time up to 3 years? |
Compliance (19) | Unclear risk | Compliance not reported |
Valid outcome measures (20) | Unclear risk | Questionnaire of subjective symptoms |
Selection bias (population) (21) | Low risk | Participants and controls were recruited from the same population |
Selection bias (time) (22) | Unclear risk | Interviews of the study group and control group were probably performed at the same time |
Random sequence generation (selection bias) | High risk | Not done |
Allocation concealment (selection bias) | High risk | Not done |
Adjustment for confounding (25) | High risk | Not done |
Incomplete outcome data (26) (attrition bias) | High risk | Medians of symptom scores were reported in each intervention group |