Table 1. Blood and Urine Chemistry in the Experimental Groups.
Variable | Sham | Aldo | Ep.+Aldo |
---|---|---|---|
Plasma aldosterone, pmol/L | 1,315.11±10.22 | 6,234.33±92.88a | 6,288.55±87.47a |
Plasma sodium, mmol/L | 141.32±1.48 | 142.17±6.32 | 140.22±4.82 |
Plasma potassium, mmol/L | 3.53±0.22 | 3.58±0.26 | 3.49±0.28 |
Plasma chloride, mmol/L | 102.64±1.34 | 102.31±2.91 | 102.42±2.62 |
Plasma bicarbonate, mmol/L | 24.71±1.14 | 24.29±1.58 | 24.48±1.64 |
Plasma creatinine, mg/dL | 0.24±0.02 | 0.24±0.02 | 0.24±0.03 |
Blood urea nitrogen, mg/dL | 19.22±1.64 | 20.48±3.28 | 20.25±2.68 |
Ratio of plasma sodium to potassium | 41.27±3.64 | 39.87±2.94 | 40.38±2.87 |
Ratio of urinary sodium to potassium | 0.32±0.02 | 0.32±0.02 | 0.32±0.03 |
Values are expressed as mean±standard deviation.
Aldo, aldosterone; Ep., eplerenone (n=6/group).
aP<0.001 compared with the sham group.