Figure 7.

Effects of maltol pretreatment on the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) signaling pathway against APAP-induced liver injury. (A) The protein expression levels of phosphorylated and total PI3K and Akt were measured by western blotting with specific primary antibodies, and β-actin protein was used as a loading control. (B,C) Quantification of relative protein expression levels was performed by densitometric analysis. All data are expressed as mean ± S.D., n = 8. ** p < 0.01 vs normal group; ## p < 0.01, # p < 0.05 vs. APAP group.