Table 4.
Pathways enriched with differentially expressed genes in the livers and jejunum mucosa of pigs induced by feeding one time daily when compared with feeding twice daily 1.
| Organ | KEGG Category | KEGG Name | GO Term | Gene | Change | % Associated Genes | p Value | q Value |
|---|---|---|---|---|---|---|---|---|
| jejunal mucosa | Metabolism | Amino acid metabolism | Glycine, serine, and threonine metabolism | ALAS2 | Down | 20.51 | <0.0001 | 0.024 |
| BPGM | Down | |||||||
| GATM | Down | |||||||
| GLDC | Down | |||||||
| GLYCTK | Up | |||||||
| PGAM2 | Down | |||||||
| PHGDH | Down | |||||||
| PSAT1 | Down | |||||||
| Organismal Systems | Digestive system | Vitamin digestion and absorption | RBP2 | Up | 27.27 | <0.0001 | 0.041 | |
| PLB1 | Up | |||||||
| APOA1 | Up | |||||||
| APOA4 | Up | |||||||
| APOB | Up | |||||||
| LRAT | Up | |||||||
| Fat digestion and absorption | FABP1 | Up | 27.03 | <0.0001 | <0.001 | |||
| AGPAT2 | Up | |||||||
| APOA1 | Up | |||||||
| MTTP | Up | |||||||
| APOA4 | Up | |||||||
| PLA2G2F | Down | |||||||
| APOB | Up | |||||||
| NPC1L1 | Up | |||||||
| GOT2 | Up | |||||||
| MOGAT2 | Up | |||||||
| Endocrine system | PPAR signaling pathway | FABP1 | Up | 15.49 | <0.0001 | 0.014 | ||
| PCK1 | Up | |||||||
| SCD | Up | |||||||
| ACAA1 | Up | |||||||
| APOA1 | Up | |||||||
| APOC3 | Up | |||||||
| PLIN2 | Down | |||||||
| SLC27A4 | Up | |||||||
| PLIN1 | Down | |||||||
| ACSL3 | Up | |||||||
| ACSL5 | Up | |||||||
| Immune system | Hematopoietic cell lineage | CD22 | Down | 13.64 | <0.0001 | 0.023 | ||
| CD19 | Down | |||||||
| CD3D | Up | |||||||
| IL1R2 | Down | |||||||
| MS4A1 | Down | |||||||
| TNF | Down | |||||||
| FCGR1A | Down | |||||||
| FCER2 | Down | |||||||
| CD14 | Down | |||||||
| CD1.1 | Down | |||||||
| IL6R | Down | |||||||
| CD1C | Down | |||||||
| Liver | Metabolism | Amino acid metabolism | Arginine biosynthesis | ARG2 | Up | 15.79 | 0.0012 | 0.022 |
| GPT2 | Up | |||||||
| NAGS | Up |
1 Values are expressed as the expression of genes in the feeding two times daily (M2) group/expression of genes in the feeding one time daily (M1) group. GO: gene ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes.