Table 2.
Phase 1 Study | ||
---|---|---|
Parameters | CONT 60 | HF 60 |
Glucose (mg·dL−1) | 83.3 ± 3.1 | 120.2 ± 8.0* |
Insulin (µUi·mL−1) | 32.9 ± 2.6 | 38.5 ± 3.6 |
HOMA-IR (mmol·L−1) | 6.7 ± 0.5 | 11.3 ± 1.2* |
TC (mg·dL−1) | 47.6 ± 2.0 | 58.1 ± 2.1* |
TG (mg·dL−1) | 27.1 ± 1.9 | 31.7 ± 4.4* |
AST (U·L−1) | 133.1 ± 8.4 | 216.2 ± 10.5* |
ALT (U·L−1) | 40.0 ± 3.2 | 48.4 ± 6.2 |
Values are expressed as means ± SD. The symbol* denotes difference from CONT 60 at a p < 0.05 significance level. CONT 60: control group fed the standard feed AIN-93G; HF 60: high-fat group fed the hyperlipidemicfeed. Animals (n = 36) were fed for 60 days. HOMA-IR: insulin resistance assessment by homeostatic model assessment; TC: total cholesterol; TG: triglycerides; AST: aspartate aminotransferase; ALT: alanine aminotransferase.