Table 3.
Phase 2 Study | ||||
---|---|---|---|---|
Biochemical Parameters | CONT 80 | CONT 80+BET | HF 80 | HF 80+BET |
Glucose (mg·dL−1) | 124.9 ± 12.3a | 112.6 ± 16.5a | 137.2 ± 23.4b | 106.6 ± 8.3a |
Insulin (µUi·mL−1) | 42.7 ± 5.3a | 36.7 ± 6.9a | 59.8 ± 4.9b | 39.4 ± 7.1a |
HOMA-IR (mmol·L−1) | 13.2 ± 2.3a | 10.2 ± 2.1a | 20.4 ± 4.9b | 10.9 ± 1.7a |
TC (mg·dL−1) | 43.7 ± 7.7a | 45.7 ± 3.9a | 69.7 ± 10.8b | 71.7 ± 5.5b |
TG (mg·dL−1) | 20.3 ± 5.1a | 19.6 ± 3.1a | 38.8 ± 8.6b | 28.6 ± 5.9a |
AST (U·L−1) | 193.0 ± 74.5a | 172.0 ± 49.5a | 265.5 ± 60.3b | 137.6 ± 27.3a |
ALT (U·L−1) | 68.4 ± 2.8a | 56.1 ± 10.4b | 78.2 ± 7.3c | 37.6 ± 7.2b |
Values are expressed as means ± SD. Different letters on the same line indicate differences between CON T80, CONT 80+BET, HF 80, and HF 80+BET at a p < 0.05 significance level. CONT 80: control group fed the standard feed AIN-93M; CONT 80+BET: control group fedthe standard feed plus betanin (20 mg·kg−1); HF 80: high-fat group fed the hyperlipidemic feed; HF 80+BET: high-fat group fed the hyperlipidemic feed plus betanin (20 mg·kg−1). HOMA-IR: insulin resistance assessment by homeostatic model assessment; TC: total cholesterol; TG: triglycerides; AST: aspartate aminotransferase; ALT: alanine aminotransferase.