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Dependence of cytotoxicity and growth inhibition potency of ArN→O and quinones on their single-electron reduction midpoint potential. (A) Cytotoxicity of ArN→O (triangles) and quinones (circles) in MH22a cells. (B) Growth inhibition potency of ArN→O (triangles) and quinones (circles) HCT-116 cells. The numbers of compounds correspond to those in Table 1. The cytotoxicity and growth inhibition potency of ArN→0 and quinones is described by the first order polynomial regressions.
