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Effects of dicoumarol on the cytotoxicity of quinones and ArN→O in MH22a cells. 50 µM tetramethyl-1,4-benzoquinone (1,2), 5.0 µM 9,10-phenanthrene quinone (3,4), 50 µM TPZ (5,6), 10 µM 7-F-TPZ (7,8) in the absence (1,3,5,7) and in the presence of 20 µM dicoumarol (2,4,6,8). This dicoumarol concentration did not affect the cell viability in control experiments, 98.5–99.3%. n = 3, p < 0.02 for 1 against 2, 5 against 6, and 7 against 8 (*), p < 0.01 for 3 against 4 (**).
