Table 1.

Scheme of case (CA) and controls (CT) pool definitions, and of genotyping.

CASES			CONTROLS
Biological	Technical		Biological	Technical
Bio_rep a	Pool_Rep b	Array_Rep c	Bio_rep a	Pool_Rep b	Array_Rep c
CA_1	CA1_A	CA_1A_1	CT_1	CT1_A	CT_1A_1
		CA_1A_2			CT_1A_2
		CA_1A_3			CT_1A_3
	CA1_B	CA_1B_1		CT1_B	CT_1B_1
		CA_1B_2			CT_1B_2
		CA_1B_3			CT_1B_3
CA_2	CA2_A	CA_2A_1	CT_2	CT2_A	CT_2A_1
		CA_2A_2			CT_2A_2
		CA_2A_3			CT_2A_3
	CA2_B	CA_2B_1		CT2_B	CT_2B_1
		CA_2B_2			CT_2B_2
		CA_2B_3			CT_2B_3
			CT_3	CT3_A	CT_3A_1
					CT_3A_3
					CT_3A_3
				CT3_B	CT_3B_1
					CT_3B_3
					CT_3B_3

^a Bio_rep = biological replicate; ^b Pool_Rep = technical pooling replicate; ^c Array_Rep = technical array replicate.