Table 1.
Patients’ demographic data and clinical characteristics grouped according to 6-week mortality.
| All (n = 131) | 6-Week Mortality (n = 25) | 6-Week Survival (n = 106) | p-value | |
|---|---|---|---|---|
| Age | 54.45 ± 14.20 | 53.88 ± 13.66 | 54.58 ± 14.39 | NS (0.842) |
| Sex (male/female) | 109/22 | 20/5 | 89/17 | NS (0.634) |
| Etiology (alcohol/virus/mixed type/others) | 51/67/12/1 | 13/10/2/0 | 38/57/10/1 | NS (0.550) |
| mNUTRIC score | 3.88 ± 2.22 | 6.27 ± 1.39 | 3.32 ± 2.01 | <0.001 |
| High mNUTRIC score | 50/131 (38.2) | 23/25 (92.0) | 27/106 (25.5) | <0.001 |
| BMI | 24.12 ± 4.24 | 24.41 ± 5.01 | 24.05 ± 4.06 | NS (0.729) |
| Child–Pugh score | 9.65 ± 2.34 | 12.48 ± 1.74 | 8.98 ± 1.93 | <0.001 |
| Child A/B/C | 12/51/68 | 0/1/24 | 12/50/44 | <0.001 |
| SOFA score | 7.57 ± 3.55 | 9.84 ± 3.83 | 6.65 ± 2.98 | <0.001 |
| APACHE II | 20.57 ± 8.34 | 29.68 ± 8.76 | 18.42 ± 6.64 | <0.001 |
| MELD | 18.92 ± 10.23 | 31.88 ± 11.48 | 15.86 ± 7.07 | <0.001 |
| CRP (mg/L) | 37.30 ± 38.00 | 60.41 ± 52.82 | 32.00 ± 31.84 | 0.003 |
| Albumin (g/dL) | 2.59 ± 0.55 | 2.42 ± 0.61 | 2.63 ± 0.52 | NS (0.080) |
| Bilirubin (mg/dL) | 5.28 ± 7.62 | 13.49 ± 13.08 | 3.35 ± 3.61 | <0.001 |
| INR | 1.81 ± 1.18 | 2.90 ± 2.15 | 1.55 ± 0.38 | <0.001 |
| Serum creatinine (mg/dL) | 1.68 ± 1.49 | 2.82 ± 1.83 | 1.41 ± 1.27 | <0.001 |
| Hemoglobulin (g/dL) | 8.43 ± 1.55 | 8.58 ± 1.96 | 8.41 ± 1.48 | NS (0.673) |
| Platelet (×109/L) | 65.02 ± 35.49 | 56.08 ± 32.66 | 67.15 ± 35.95 | NS (0.162) |
| Leukocytes (×109/L) | 9.43 ± 6.08 | 12.25 ± 9.01 | 8.75 ± 4.96 | 0.009 |
| Blood transfusion (unit) | 4.56 ± 4.01 | 8.75 ± 5.04 | 3.65 ± 3.13 | <0.001 |
| Mean arterial pressure (mmHg) | 73.91 ± 12.87 | 64.22 ± 11.12 | 76.31 ± 12.17 | 0.003 |
| Shock (%) | 59/131 (45.0) | 22/25 (88.0) | 37/106 (34.9) | <0.001 |
| Ascites (%) | 83/131 (63.4) | 24/25 (96.0) | 59/106 (55.7) | 0.001 |
| Hepatic encephalopathy (%) | 73/131 (55.7) | 20/25 (80.0) | 53/106 (50.0) | 0.007 |
| Hepatocellular carcinoma (%) | 33/131 (25.2) | 9/25 (36.0) | 24/106 (22.6) | NS (0.166) |
| Bacterial infection at inclusion (%) | 42/131 (32.1) | 19/25 (76.0) | 23/106 (21.7) | <0.001 |
| Treatment failure (%) | 38/131 (29.0) | 20/25 (80.0%) | 18/106 (17.0%) | <0.001 |
| ICU stay (days) | 8.05 ± 8.54 | 12.76 ± 11.04 | 6.91 ± 7.47 | 0.002 |
Abbreviations: mNUTRIC, Modified Nutrition Risk in the Critically Ill; BMI, body mass index; SOFA, Sequential Organ Failure Assessment; APACHE II, Acute Physiology and Chronic Health Evaluation II; MELD, Model for End-Stage Liver Disease; CRP, C-reactive protein; INR, international normalized ratio; ICU, intensive care unit; NS, non-significant.