Table 3.
Patients’ demographic data and clinical characteristics grouped according to modified NUTRIC score.
| All (n = 131) | High mNUTRIC (n = 50) | Low mNUTRIC (n = 81) | p-value | |
|---|---|---|---|---|
| Age | 54.45 ± 14.20 | 60.62 ± 13.51 | 50.64 ± 13.33 | <0.001 |
| Sex (male/female) | 109/22 | 38/12 | 71/10 | NS (0.083) |
| Etiology (alcohol/virus/mixed type/others) | 51/67/12/1 | 17/30/3/0 | 34/37/9/1 | NS (0.359) |
| BMI | 24.12 ± 4.24 | 24.51 ± 4.21 | 23.87 ± 4.27 | NS (0.448) |
| Child–Pugh score | 9.65 ± 2.34 | 11.00 ± 2.28 | 8.81 ± 1.97 | <0.001 |
| Child A/B/C | 12/51/68 | 1/12/37 | 11/39/31 | <0.001 |
| SOFA score | 7.57 ± 3.55 | 10.40 ± 3.42 | 5.83 ± 2.29 | <0.001 |
| APACHE II | 20.57 ± 8.34 | 27.90 ± 7.47 | 16.05 ± 4.95 | <0.001 |
| MELD | 18.92 ± 10.23 | 26.22 ± 11.04 | 14.41 ± 6.44 | <0.001 |
| CRP (mg/L) | 37.30 ± 38.00 | 53.97 ± 43.46 | 26.09 ± 29.21 | <0.001 |
| Albumin (g/dL) | 2.59 ± 0.55 | 2.49 ± 0.53 | 2.65 ± 0.55 | NS (0.091) |
| Bilirubin (mg/dl) | 5.28 ± 7.62 | 7.69 ± 9.88 | 3.80 ± 5.37 | 0.004 |
| INR | 1.81 ± 1.18 | 2.24 ± 1.67 | 1.54 ± 0.38 | <0.001 |
| Serum creatinine (mg/dL) | 1.68 ± 1.49 | 2.68 ± 1.84 | 1.06 ± 0.72 | <0.001 |
| Hemoglobulin (g/dL) | 8.43 ± 1.55 | 8.45 ± 1.51 | 8.42 ± 1.59 | NS (0.924) |
| Platelet (x109/L) | 65.02 ± 35.49 | 63.53 ± 33.08 | 65.92 ± 37.04 | NS (0.711) |
| Leukocytes (x109/L) | 9.43 ± 6.08 | 11.57 ± 7.76 | 8.12 ± 4.32 | 0.002 |
| Blood transfusion (unit) | 4.56 ± 4.01 | 5.17 ± 4.71 | 4.15 ± 3.44 | NS (0.243) |
| Mean arterial pressure (mmHg) | 73.91 ± 12.87 | 68.24 ± 11.82 | 77.41 ± 12.30 | <0.001 |
| Shock (%) | 59/131 (45.0) | 28/50 (56.0) | 31/81 (38.3) | 0.048 |
| Ascites (%) | 83/131 (63.4) | 39/50 (78.0) | 44/81 (54.3) | 0.006 |
| Hepatic encephalopathy (%) | 73/131 (55.7) | 33/50 (66.0) | 40/81 (49.4) | NS (0.063) |
| Hepatocellular carcinoma (%) | 33/131 (25.2) | 21/60 (42.0) | 12/81 (14.8) | <0.001 |
| Bacterial infection at inclusion (%) | 42/131 (32.1) | 23/50 (46.0) | 19/81 (23.5) | 0.007 |
| Outcome | ||||
| Treatment failure (%) | 38/131 (29.0) | 24/50 (48.0) | 14/62 (17.3) | <0.001 |
| ICU stay (days) | 8.05 ± 8.54 | 11.20 ± 10.56 | 6.05 ± 6.26 | 0.001 |
| ICU mortality (%) | 26/131 19.8) | 23/50 (46.0) | 3/81 (3.7) | <0.001 |
| 28-day mortality (%) | 23/131 (17.6) | 21/50 (42.0) | 2/81 (2.5) | <0.001 |
| 6-week mortality (%) | 25/131 (19.1) | 23/50 (46.0) | 2/81 (2.5) | <0.001 |
Abbreviations: mNUTRIC, modified nutrition risk in the critically ill; BMI, body mass index; SOFA, Sequential Organ Failure Assessment; APACHE II, Acute Physiology and Chronic Health Evaluation II MELD, Model for End-Stage Liver Disease; CRP, C-reactive protein; INR, international normalized ratio; ICU, intensive care unit.