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. 2019 Sep 17;20(18):4590. doi: 10.3390/ijms20184590

Figure 2.

Figure 2

DC/DCleu-generation from leukemic whole blood (WB). (A) shows average amounts ± standard deviation of DC- and DCleu-proportions [including DCleu-subgroups: DCleu in the DC-fraction (DCleu/DC+), DCleu in the blast-fraction (to quantify amounts of leukemic blasts converted to DCleu) (DCleu/Bla+) and DCleu in the WB-fraction (DCleu/WB)] from leukemic WB with Kits (including Kit M, Kit K, Kit I) compared to protocols Picis (including Pici-PGE1, Pici-PGE2). (B) shows average amounts ± standard deviation of generated DCs with Kit M, Kit K and Kit I compared to control. (C) presents average amounts ± standard deviation of generated DCleu subgroups [including DCleu-subgroups DCleu in the DC-fraction (DCleu/DC+), DCleu in the blast-fraction (to quantify amounts of leukemic blasts converted to DCleu) (DCleu/Bla+) and DCleu in the WB-fraction (DCleu/WB)] with Kit M, Kit K and Kit I. (D) shows average amounts ± standard deviation of DCmig/DC+ generated with Kit M, Kit K and Kit I. DCmig are characterized by the expression of CCR7. DCs dendritic cells; DCleu leukemic derived dendritic cells; WB whole blood. The differences were considered as significant*, with p values between 0.1 and 0.05 and as significant*** with p values <0.005.