Table 2.
Effect of djulis on 1,2-dimethyl hydrazine (DMH)-induced aberrant crypt foci (ACF) (number/cm2) according to various sizes of crypts in the colon of male F344 rats 1.
| Group 2 | Number of Focus Containing | Small ACF | Large ACF | ||
|---|---|---|---|---|---|
| 1 crypt | 2 crypts | 3 crypts | (≤3 crypts) | (≥4 crypts) | |
| DMH | 1.3 ± 0.6 a | 2.9 ± 0.9 a | 2.6 ± 0.7 a | 6.7 ± 1.1 a | 1.0 ± 0.6 |
| LD | 0.9 ± 0.4 b | 1.9 ± 0.7 b | 1.0 ± 0.3 bc | 3.8 ± 1.1 b | 0.7 ± 0.3 |
| MD | 0.6 ± 0.2 bc | 1.5 ± 0.4 b | 1.3 ± 0.4 b | 3.4 ± 0.5 bc | 0.9 ± 0.4 |
| HD | 0.4 ± 0.2 c | 1.5 ± 0.4 b | 0.8 ± 0.3 c | 2.7 ± 0.5 c | 0.7 ± 0.4 |
1 All values are the mean ± SD (n = 9). Values followed by different superscripts within the same column are significantly different (p < 0.05) determined by a one-way ANOVA followed by Duncan’s multiple-range test, p < 0.05. 2 All rats were administered 1,2-dimethyl hydrazine (DMH). DMH, AIN-93G diet; LD, AIN-93G diet containing 5% djulis; MD, AIN-93G diet containing 10% djulis; HD, AIN-93G diet containing 20% djulis.