Table 4.
TCRγδ+ cells in CD patients following a long-term GFD.
| Study | Sample Size | Time on a GFD | Mean Age (Years) | TCRγδ+ Cut-Off for CD | Baseline TCRγδ+ IEL (%) | After-GFD TCRγδ+ IEL (%) |
|---|---|---|---|---|---|---|
| Calleja [14] | 21 | 1 year | Adults | >12% | Mean (SEM), 24.9 (3.3) (100% Marsh 3) |
Mean (SEM), 25.7 (3.0) (14% Marsh 3a) |
| Saborido [26] | 30 | 5.4 ± 1.6 years | Mean 10.3 (range, 6–18) | >10% | Mean (SD), 35.9 (16.4); Median, 36.5 (IQR, 25–75) (0% Marsh 3) |
|
| Camarero [15] | 14 | >2 years | Mean 7 (range, 3–14) | >10% | Median, 22 (IQR, 19–36) (0% Marsh 3) |
|
| Rosinach [28] | 18 | >1 year | Mean 25 (range, 5–65) | >8.5% | Mean (SEM), 25.1 (2.4) (100% Marsh 3) |
Mean (SEM), 28.2 (2.6) (16% Marsh 3) |
| Nijeboer [27] | 118 | NA | Median 53 (range, 12–79) |
>13% | Median, 19 (0% Marsh 3) |
NA: Not available GFD: Gluten-free diet.