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. 2019 Sep 7;11(9):2144. doi: 10.3390/nu11092144

Figure 2.

Figure 2

Effect of mutant TP53 expression on iron-related gene expression. Relative mRNA expression of (A) iron–sulfur cluster assembly enzyme 1 (ISCU1), (B) transferrin receptor 1 (TFRC), (C) N-MYC downstream regulated gene 1 (NDRG1), and (D) heme oxygenase 1 (HMOX1) in TP53 null H1299 cells (H1299) or H1299 cells transfected with wild-type (WT) TP53, or the indicated mutant TP53. * Denotes statistical difference from H1299. Superscripts (a,b,c) denote statistical significance between mutation types, p < 0.05. Treatments that share the same superscripts are not significantly different.