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. 2019 Sep 8;8(9):1054. doi: 10.3390/cells8091054

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Associations of the expression of hub genes with survival prognosis in colorectal cancer (CRC) patients. (A). Kaplan-Meier curves show that three hub genes (COL5A2, EDNRA, and OLR1) had a negative expression correlation with survival prognosis (overall survival (OS) and/or disease-free survival (DFS)) in CRC by Prognoscan (log-rank test, p < 0.05). (B). Kaplan-Meier curves shows that the elevated expression of four hub genes (COL5A2, EDNRA, OLR1, and TGFBI) is associated with a worse DFS prognosis in the TCGA colon cancer cohort by GEPIA [23] (log-rank test, p < 0.05).

Associations of the expression of hub genes with survival prognosis in colorectal cancer (CRC) patients. (A). Kaplan-Meier curves show that three hub genes (COL5A2, EDNRA, and OLR1) had a negative expression correlation with survival prognosis (overall survival (OS) and/or disease-free survival (DFS)) in CRC by Prognoscan (log-rank test, p < 0.05). (B). Kaplan-Meier curves shows that the elevated expression of four hub genes (COL5A2, EDNRA, OLR1, and TGFBI) is associated with a worse DFS prognosis in the TCGA colon cancer cohort by GEPIA [23] (log-rank test, p < 0.05).