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Linear vs Circular splicing. Circular RNAs (circRNAs) are formed from an unusual splicing event that results in covalently linked 3′–5′ ends termed as a backsplice junction (top, indicated by a red arrow). As for linear transcripts (bottom), circRNAs can undergo alternative splicing, resulting in different classes of transcripts (mono or multi exonic, intronic, exon-intron structure).
