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. 2019 Sep 17;20(18):4592. doi: 10.3390/ijms20184592

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Biologically active metabolites of AGXT2. ADMA: asymmetric dimethyarginine; ADGV: asymmetric α-keto-dimethylguanidinovaleric acid; SDMA: symmetric dimethylarginine; SDGV: symmetric α-keto-dimethylguanidinovaleric acid; GOCA: 6-guanidino-2-oxocaproic acid; BAIBA: beta-aminoisobutyric acid. Alanine and glyoxylate (another substrates of AGXT2) are intentionally not included in the figure, as it is not clear whether AGXT2 plays a biologically significant role in regulation of their levels.