Table 1.
Parameters | DR Rats | DS Rats | ||||
---|---|---|---|---|---|---|
Normal Salt (DR/N) |
High Salt (DR/H) |
Normal Salt (DS/N) |
High Salt (DS/H) |
High Salt + Tempol (DS/H + Tempol) | High Salt + Eplerenone (DS/H + Eplerenone) | |
SBP, mmHg | 101.7 ± 4.5 | 110 ± 2.6 | 124.5 ± 2.4 | 160.8 ± 9.2 aa | 121.2 ± 7.4 bb | 132.2 ± 3.4 b |
BW, g | 364.8 ± 4.4 | 354.5 ± 3.6 | 336.5 ± 3.3 | 316 ± 5.4 aa | 308.2 ± 6.9 | 296 ± 7.4 bb |
Left KW, mg/g BW | 3.6 ± 0.1 | 3.3 ± 0.06 | 3.9 ± 0.09 | 5.2 ± 0.13 aa | 5.4 ± 0.16 | 4.2 ± 0.06 bb |
BW, body weight; KW, kidney weight; SBP, systolic blood pressure. Data are expressed as means ± SE. DR, Dahl salt-resistant; DS, Dahl salt-sensitive. aa p < 0.01 vs. same strain on a normal-salt diet. b p < 0.05, bb p < 0.01 vs. vehicle.