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Box plot of rat grimace score. Maximum obtainable score was 8. Statistical comparison within group across time not shown (refer to Table 2). Saline + Saline (n = 11), 5-FU + Saline (n = 12), 5-FU + Fentanyl (n = 12), 5-FU + Morphine (n =12) and 5-FU + Oxycodone (n = 12) at all time-points.
