. 2019 Sep 3;11(9):2070. doi: 10.3390/nu11092070

Table 5.

Meta-analyses of height-for-age z-scores in children with phenylketonuria.

Age (Year)	NoS	NoP Tested	Effect Size	Heterogeneity I², P	95% CI	P
0	3 ^a	488	−0.192	I² = 93.2%, P = 0.0001	−0.466 to +0.081	0.168
0.5	2 ^b	361	−0.157	I² = 97.1%, P = <0.0001	−0.447 to +0.133	0.290
1	3 ^a	459	−0.422	I² = 96.7%, P = <0.0001	−0.672 to −0.173	<0.001
1.5	2 ^b	361	−0.629	I² = 85.8%, P = 0.008	−0.735 to −0.522	<0.0001
2	3 ^a	500	−0.646	I² = 90.9%, P = <0.0001	−0.787 to −0.505	<0.0001
2.5	2 ^b	361	−0.661	I² = 55.78%, P = 0.133	−0.718 to −0.603	<0.0001
3	3 ^a	505	−0.566	I² = 72.9%, P = 0.014	−0.649 to −0.484	<0.0001
3.5	2 ^b	361	−0.470	I² = 63.3%, P = 0.099	−0.543 to −0.397	<0.0001
4	3 ^a	497	−0.493	I² = 0.0%, P = 0.819	−0.519 to −0.468	<0.0001
4.5	2 ^b	361	−0.539	I² = 80.3%, P = 0.024	−0.630 to −0.447	<0.0001
5	3 ^a	497	−0.467	I² = 22.0%, P = 0.184	−0.507 to −0.427	<0.0001
5.5	2 ^b	361	−0.439	I² = 74.1%, P = 0.050	−0.519 to −0.360	<0.0001
6	3 ^a	491	−0.462	I² = 90.4%, P = 0.015	−0.605 to −0.320	<0.0001
7	2^c	409	−0.464	I² = 24.8%, P = 0.249	−0.535 to −0.393	<0.0001
8	2 ^c	399	−0.444	I² = 69.2%, P = 0.071	−0.598 to −0.291	<0.0001
9	2 ^c	400	−0.491	I² = 94.3%, P = <0.0001	−0.843 to −0.139	0.006
10	2 ^c	399	−0.400	I² = 91.3%, P = 0.0007	−0.672 to −0.127	0.004
11	2^c	376	−0.286	I² = 73.4%, P = 0.053	−0.460 to −0.112	<0.001
12	2 ^c	388	−0.338	I² = 63.0%, P = 0.100	−0.479 to −0.197	<0.0001
13	2 ^c	372	−0.376	I² = 0.0%, P = 0.381	−0.413 to −0.339	<0.0001
14	2 ^c	379	−0.438	I² = 50.4%, P = 0.156	−0.550 to −0.327	<0.0001
15	2 ^c	365	−0.450	I² = 66.7%, P = 0.083	−0.608 to −0.292	<0.0001
16	2 ^c	374	−0.524	I² = 0.0%, P = 0.541	−0.562 to −0.486	<0.0001
17	2 ^c	362	−0.642	I² = 0.0%, P = 0.946	−0.688 to −0.597	<0.0001
18	2 ^c	352	−0.842	I² = 0.0%, P = 0.863	−0.906 to −0.777	<0.0001

NoS: number of studies; NoP: number of patients; CI: confidence interval. References ^a Schaefer et al., 1994 [20], Aldámiz-Echevarría et al., 2014 [31], Thiele et al., 2017 [32]; ^b Schaefer et al., 1994 [20], Aldámiz-Echevarría et al., 2014 [31]; ^c Aldámiz-Echevarría et al., 2014 [31], Thiele et al., 2017 [32].