Table 1.
Baseline characteristics of IBD patients and healthy controls (HC).
| Variables | HC | IBD | P-Value |
|---|---|---|---|
| n = 50 | n = 78 | ||
| Serum free thiols per gram of albumin (µmol/g) | 21.1 ± 1.9 | 18.5 ± 3.4 | <0.001 |
| Age (years) | 50.7 ± 8.5 | 43.3 ± 8.5 | <0.01 |
| Female, n (%) | 23 (46.0) | 36 (46.2) | 0.99 |
| BMI (kg/m2) | 26.9 ± 3.1 | 24.8 ± 4.9 | <0.01 |
| Current smoking, n (%) | 13 (26.0) | 13 (18.8) | 0.35 |
| Laboratory Measurements | |||
| Hemoglobin (g/dL) | 14.8 ± 1.3 | 12.3 ± 1.8 | <0.001 |
| CRP (mg/L) * | 1.0 (0.6–1.5) | 4.1 (1.2–10.3) | <0.001 |
| WBC (×109/L) * | 6.7 (5.4–7.8) | 7.6 (6.0–10.3) | <0.01 |
| Platelets (×109/L) * | 244 (207–296) | 308 (259–376) | <0.001 |
| Albumin (g/L) | 45.6 ± 2.3 | 40.1 ± 3.9 | <0.001 |
| eGFR (mL/min * 1.73m2) | 87.7 ± 14.5 | 102.4 ± 26.4 | <0.01 |
| Creatinine (µmol/L) | 81.5 ± 15.9 | 73.1 ± 21.1 | <0.05 |
Data are presented as mean ± SD or proportions (n, %). * Skewed data are presented as median (interquartile range). P-values were two-tailed and calculated using independent sample t-tests or Mann–Whitney U-tests, as appropriate. Abbreviations: IBD, inflammatory bowel disease; CD, Crohn’s disease; HC, healthy controls; BMI, body mass index; CRP, C-reactive protein; WBC, white blood cell count; eGFR, estimated glomerular filtration rate. Bold P-values indicate statistical significance.