Table 4.
Evolution in absolute counts of cluster differentiation (CD) markers.
| Cluster Differentiation Markers Counts | |||||||
|---|---|---|---|---|---|---|---|
| CC (Control) | CR (Study) | Effect * | |||||
| V1 | V3 | V1 | V3 | Visit | Group | Visit × Group | |
| CD45+ (cs/mL) | 6458.99 (457.29) | 6231.24 (474.55) | 6260.18 (403.99) | 7764.86 (378.69) | 0.0491 | 0.2578 | 0.0207 |
| CD3+ (cs/mL)∆ | 1615.72 (124.1) | 1744.94 (140.34) | 1581.5 (93.34) | 2012.5 (161.31) | 0.0018 | 0.5577 | 0.0678 |
| CD4+ (cs/mL)∆ | 960.67 (66.18) | 1045.5 (77.89) | 902.11 (59.85) | 1149.33 (89.98) | <0.001 | 0.9008 | 0.0714 |
| CD8+ (cs/mL) ∆ | 526.94 (68.13) | 555.56 (63.82) | 524.28 (36.67) | 667.11 (62.62) | 0.0047 | 0.5025 | 0.0563 |
| CD14+ (cs/mL) | 473.06 (39.68) | 471.22 (40.84) | 409.94 (28.53) | 565.72 (42.81) | 0.0144 | 0.7858 | 0.0126 |
| CD16+ (cs/mL) | 3485.56 (362.15) | 3183.78 (310.67) | 3253.83 (274.68) | 3935.72 (224.94) | 0.365 | 0.3393 | 0.0318 |
| CD56+ (cs/mL) | 429.61 (51.53) | 407.78 (46.1) | 415.33 (40.05) | 516.11 (50.95) | 0.2417 | 0.4904 | 0.0716 |
* Effect: Visit indicates the evolution in the same group from the beginning to the end of the intervention; group indicates the differences between groups regardless of time; and visit × group indicates the differences in evolution between groups as a result of the treatment received (CC or CR). The p-value of the interaction was adjusted by sex, age, and BMI. Data expressed as mean (SEM). A p-value > 0.05 was considered non-significant. Analysis performed on a subsample (n = 18) for group CC and (n = 18) for group CR. ∆ Counts on CD45+.