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. 2019 Aug 31;11(9):1282. doi: 10.3390/cancers11091282

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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An example of a 46-year-old patient with pluri-metastatic intestinal neuroendocrine tumor (grade 2, ki67 at 4%). 68Ga DOTA-TOC (A), FDG-PET (18F-fluoro-deoxyglucose- positron-emission-tomography) (B) and FDOPA (18F-fluorodihydroxyphenylalanine) (C) imaging were realized. MIP (maximum intensity projections) images from the respective PET data sets are shown. The subject has positive on both FDOPA and somatostatine-receptor imaging, dominant disease which exhibits no FDG uptake (green arrows). One hepatic lesion was FDOPA-negative and 68Ga-DOTA-TOC-positive (red arrow) and one gastric lesion was FDOPA-positive and 68Ga-DOTA-TOC negative (blue arrow). Images courtesy of Pr C. Bodet-Milin.