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. 2019 Sep 9;11(9):1336. doi: 10.3390/cancers11091336

Table 1.

Inhibitory effects of Piper genus-derived compounds on human cancer cell viability.

Compound IC50 (μg/mL)
U373 Cells MCF7 Cells
Gibbilimbol B 16.79 16.44
Eriopodol A 11.12 10.12
Eriopodol B 31.91 29.36
Eriopodol C 14.30 16.30
Erioquinol 1.78 2.63

3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was performed treating cells for 24 h in the absence (vehicle) or in the presence of increasing concentrations of Piper genus-derived compounds. The results have been obtained in four independent experiments.