Table 1.

Values for weight, proteinuria, creatininuria, creatininemia, creatinine clearance, and fractional excretion (FE) for Na+ and K+ in the experimental groups. Protein and creatinine were measured to assess renal function; the fractional excretion of sodium and potassium (FENa+, FEK+, [%]) was also determined. Data are expressed as mean ± SE. The differences were evaluated by analysis of variance followed by the Tukey post-hoc test. *** p < 0.001 vs. AngII groups (n ≥ 4/all groups).

Groups	Weigth (gr)	Proteinuria (mg/day)	Creatinine Clearence (ml/min)	FE Na + (%)	FE K + (%)
Ctrl	482 ± 31	2.7 ± 1.1 ***	1.4 ± 0.3 ***	0.2 ± 0.0 ***	12.0 ± 2.7 ***
Ctrll+fasudil	480 ± 36	3.6 ± 1.1 ***	2.1± 0.1 ***	0.1 ± 0.0 ***	12.5 ± 0.3 ***
AngII	364 ± 42	214.0 ± 19.0	0.7 ± 0.0	2.2 ± 0.4	162.0 ± 23.0
AngII+fasudil	368 ± 17	19 ± 7.2 ***	1.9 ± 0.2 ***	0.5 ± 0.1 ***	30 ± 7.2 ***