Table 3.
Baseline biomarker status.
| Study | Group | Vitamin B6 | Folate (RC) | Folate (Serum) | Vitamin B12 | Homocysteine |
|---|---|---|---|---|---|---|
| Armborst et al. (2018) | Placebo | - | - | 9.48 (3.08) | - | - |
| Active | - | - | 9.67 (4.13) | - | - | |
| Camfield et al. (2013) | Placebo | 114.08 (10.27) | 944.96 (21.94) | - | 314.60 (14.48) | 10.6137 (0.22) |
| Active | 111.70 (9.36) | 933.27 (34.99) | - | 289.25 (12.11) | 10.8444 (0.35) | |
| Cockle et al. (2000) | Placebo Males | 235.64 (75.74) | - | 9.74 (5.66) | 304.10 (160.93) | - |
| Placebo Females | 239.02 (54.95) | - | 9.31 (4.13) | 323.44 (150.06) | - | |
| Active Males | 243.74 (50.06) | - | 8.63 (3.70) | 307.26 (86.29) | - | |
| Active Females | 230.72 (46.85) | - | 9.10 (4.76) | 365.66 (156.38) | - | |
| Ford et al. (2008) | Placebo | - | - | 24.22 (7.44) | 253.30 (115.10) | 13.06 (3.83) |
| Active | - | - | 24.00 (7.50) | 253.10 (107.50) | 13.59 (4.43) | |
| Gosney et al. (2008) | Overall | - | - | 5.88 (range 0.9–39.8) | - | - |
| Hallert et al. (2009) | Placebo | - | - | 14.8 (range 7.7–23.4) | 431 (174–734) | 11.4 (7.4–21.9) |
| Active | - | - | 12.9 (range 6.7–44) | 326 (141–510) | 11.70 (7.8–23.0) | |
| Haskell et al. (2010) | Placebo | - | - | - | - | 10.93 (0.53) |
| Active | - | - | - | - | 10.94 (0.46) | |
| Oliver-Baxter et al. (2018) | Placebo | - | - | 27.1 (13.9) | - | - |
| Active | - | - | 28.2 (16.7) | - | - | |
| White et al. (2015) | Placebo | 85.00 (34.02) | 944.25 (190.09) | - | 304.88 (75.34) | 11.43(2.24) |
| Active | 84.95 (23.73) | 954.63 (188.58) | - | 301.04 (82.22) | 11.78 (1.81) |
Standard deviation/error reported in parentheses.