miRNAs	microRNAs
DM	Diabetes mellitus
T1D	Type 1 diabetes
HLA	Human leukocyte antigen
T2D	Type 2 diabetes
IR	Insulin resistance
ADA	American Diabetes Association
ED	Endothelial dysfunction
CVD	Cardiovascular diseases
PN	Peripheral neuropathy
NO	Nitric oxide
TGF	Transforming growth factor
DN	Diabetic neuropathy
DSPN	Distal symmetric polyneuropathy
DPN	Diabetic peripheral neuropathy
STZ	Streptozotocin
miRs	microRNAs
RNAi	RNA interference
AD	Alzheimer’s disease
PD	Parkinson’s disease
NF-κB	Nuclear factor κB
MCP	Monocyte chemoattractant protein
PTEN	Phosphatase and tensin homologue
VEGF	Vascular endothelial growth factor
IL	Interleukin 2
IKAK 1	Interleukin-1 receptor-associated kinase 1
TRAF6	Tumor necrosis factor receptor-associated kinase 1
ADAMTS3	A disintegrin and metalloproteinase with thrombospondin motifs 3
12/15-LOX	12/15 lipoxygenase
DRG	Dorsal root ganglia
DH	Dorsal horn
CALHM1	Calcium homeostasis modulator 1
P2X7	Purinergic receptor P2X ligand gated ion channel 7
Podxl	Podocalyxin-like
Hoxa1	Homeobox A1
SLC17A6	Solute carrier family 17A6
VGLUT2	Vesicular-glutamate transporter 2
rev	Reviewed
EVs	Extracellular vesicles
NDNMT3A	DNA target proteins methyltransferase-3a
NUMB	Endocytic adaptor protein
SNAP25	Synaptosome associated protein 25
GAP43	Growth-associated protein-43
HG	High glucose
PRKCI	Protein kinase C iota
SMAD	Small mother against decapentaplegic
CNS	Central nervous system
SNPs	Single nucleotide polymorphisms
CAN	Cardiovascular autonomic neuropathy
SERPINE2	Serine protease inhibitor E2
DEGs	Differentially expressed genes
PPAR	Peroxisome proliferator-activated receptor
AMP	Adenosine monophosphate
AMPK	AMP-activated protein kinase
PPARG	PPAR gamma
SCD	Stearoyl-CoA desaturase
CD36	Cluster of differentiation 36
PCK1	Phosphoenolpyruvate carboxykinase 1
ANXA9	Annexin A9
ANGPTL4	Angiopoietin like 4
CHI3L2	Chitinase 3 Like 2
ADRBK2	Adrenoceptor Beta 2
CSN1S1	Casein Alpha S1
GALM	Galactose mutarotase
EN1	Homeobox protein engrailed-1
FAM89A	Family with sequence similarity 89 member A