Table 1.
Oxaliplatin-induced growth inhibition: Comparison between control-siRNA and ABCC2-siRNAs-transfected cells.
| Cell Lines | Transfected Cells | IC50 * (µM) (Mean ± SEM) | p-Value |
|---|---|---|---|
| Caco-2 | Control-siRNA | 13.82 ± 1.21 | - |
| ABCC2-siRNA-1 | 7.75 ± 0.08 | 0.0001 | |
| ABCC2-siRNA-2 | 8.4 ± 0.13 | 0.0001 | |
| ABCC2-siRNA-3 | 7.03 ± 0.76 | 0.0001 | |
| PANC-1 | Control-siRNA | 35.13 ± 3.19 | - |
| ABCC2-siRNA-1 | 16.48 ± 0.53 | 0.018 | |
| ABCC2-siRNA-2 | 11.91 ± 0.25 | 0.027 | |
| ABCC2-siRNA-3 | 14.60 ± 0.72 | 0.012 |
* Data shown are mean ± standard errors of the mean from three independent experiments.