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. 2019 Sep 1;9(9):437. doi: 10.3390/biom9090437

Table 1.

IC50 values and Selectivity Index (SI) obtained with NR assay after 24 h treatment with dendrimer conjugates, native PAMAM G3, or nimesulide alone.

Compound IC50 [µM] Selectivity Index (SI)
BJ SCC-15
PAMAM G3 5.64 12.68 2.25
Nimesulide 587.30 426.90 0.72
G3B18N 14.50 5.96 0.41
G3B31N 1.99 1.60 0.80