Figure 12.

HN protects AgNPs-induced oxidative damage caused to DNA. (A) SH-SY5Y cells were pretreated with or without 10 μg/mL HN for 24 h. Cells were then treated with 10 μg/mL HN and/or 10 μg/mL AgNPs for 24 h. 8-oxo-dG was measured after 24 h of exposure of SH-SY5Y cells. (B) SH-SY5Y cells were pretreated with or without 10 μg/mL HN for 24 h. Cells were then treated with 10 μg/mL HN and/or 10 μg/mL AgNPs for 24 h. 8-oxo-G was measured after 24 h of exposure of SH-SY5Y cells. Results are expressed as mean ± standard deviation of three independent experiments. There was a significant difference in treated cells compared with untreated cells based on Student’s t-test (* p < 0.05).