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. 2019 Aug 26;9(9):414. doi: 10.3390/biom9090414

Figure 2.

Figure 2

Compound–target network of Cordyceps militaris. Rectangles represent the compounds, and circles represent the targets. Nodes related to apoptosis, estrogen, hedgehog, and notch signaling pathway in KEGG and validated targets by western blotting analysis are colored. ADA, adenosine deaminase; AHCY, adenosylhomocysteinase; ALB, albumin; BAX, BCL2 associated X, apoptosis regulator; BCL2, BCL2 apoptosis regulator; CASP8, caspase 8; GFAP, glial fibrillary acidic protein; IL1B, interleukin 1 beta; MMP1, matrix metallopeptidase 1; MMP9, matrix metalloproteinase-9; NOTCH1, notch receptor 1; OTX2, orthodenticle homeobox 2; SHH, sonic hedgehog signaling molecule; STAR, steroidogenic acute regulatory protein; TNF, tumor necrosis factor; XIAP, X-linked inhibitor of apoptosis.