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. 2019 Aug 26;9(9):414. doi: 10.3390/biom9090414

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of Cordyceps militaris concentrate (100 μg/mL) and cordycepin (25 and 50 μM) on apoptosis in MCF-7 breast cancer cells exposed for 24 h. (A) Results of Hoechst 33342 fluorescent staining of Cordyceps militaris and cordycepin to detect nuclear condensation of MCF-7 cells. (B) Protein expression of Bax, Bcl-2, cleaved caspase-7, cleaved caspase-8, XIAP and GAPDH. (C) Graph of relative protein expression. Data are the means of experiments performed in triplicate. Data are presented as the mean ± SD. and were analyzed using the Student’s t-test. *p < 0.05 versus non-treated cells.