Table 4.
Final model between nutrients and hematological parameters in adult sickle cell disease patients (n = 51).
| Antioxidant Nutrients | Hematological Parameters | R 2 | β | CI | p Value a |
|---|---|---|---|---|---|
| Selenium | LDH (U/L) | 0.62 | −13.90 | −22.79; −5.02 | 0.003 |
| ERY (1012/L) | 0.30 | 0.02 | 0.00; 0.04 | 0.010 | |
| Hb (g/dL) | 0.38 | 0.06 | 0.01; 0.10 | 0.006 | |
| HT (%) | 0.37 | 0.19 | 0.06; 0.32 | 0.006 | |
| RET (%) | 0.27 | −0.09 | −0.19; 0.00 | 0.040 | |
| TB (mg/dL) | 0.54 | −0.05 | −0.08; −0.02 | 0.001 | |
| DB (mg/dL) | 0.56 | −0.01 | −0.02; 0.00 | 0.007 | |
| IB (mg/dL) | 0.42 | −0.04 | −0.07; −0.01 | 0.007 | |
| HbF (%) | 0.41 | −0.22 | −0.40; −0.04 | 0.017 | |
| Vitamin E | RDW (%) | 0.28 | −0.26 | −0.43; −0.08 | 0.005 |
CI (confidence interval). Only significant results from the backward linear regression analysis are shown in this table. a p values obtained from the backward linear regression analysis, considering antioxidant micronutrients (vitamin A, E, selenium, and zinc) as independent variables and hematological parameters (LDH, ERY, Hb, HT, RDW, RET, TB, DB, IB, HbF, and HbS) as dependent variables. The analysis was adjusted for the following variables: skin color, age, sex, genotype, use of hydroxyurea, us-CRP, and leukocyte count.