Table 2.

Interaction between PPARα polymorphisms and diet on plasma lipoproteins.

SNP	Lipid Changes
rs1800206 C > G (Leu162Val) chr22:46218377 (GRCh38.p12)	(1) In 162V allele carriers, low PUFA diet was associated with higher plasma TG and apoC-III levels. PUFA intake >8% corresponded to a 4% lower plasma TG (2) Lower total cholesterol and apoA-I upon a high PUFA diet
rs6008259 3′UTR G > A	(1) According to n-6 fatty acid intake (low vs. high consumers), in carriers of GG or AG genotypes, high daily intake (>7.99 g/d) of linoleic acid led to higher levels of total- and LDL-C
rs3892755 3′UTR C > T	(1) According to n-3 fatty acid intake (low vs. high consumers), in carriers of CC or CT genotypes, high daily intake (>0.32 g/d) of eicosapentaenoic acid + docosahexaenoic acid led to higher levels of total- and LDL-C