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. 2019 Aug 30;10(9):666. doi: 10.3390/genes10090666

Figure 14.

Figure 14

Results of the fully automated single particle picking in cryo-EM images by the base and super-clustering methods. Red dots denote the missing particles not detected (false negatives) and yellow dots show false positives. (a) Particle picking of IBC; (b) particle picking of IBC on an extremely low SNR cryo-EM image; (c) particle picking of SP-IBC; (d) single particle picking of SP-IBC on an extremely low SNR cryo-EM image; (e) particle picking of k-means; (f) particle picking of k-means clustering algorithm on an extremely low-SNR cryo-EM image; (g) particle picking of SP-k-means; (h) particle picking of SP-k-means on an extremely low-SNR cryo-EM image; (i) particle picking of FCM; (j) particle picking of FCM on an extremely low-SNR cryo-EM image; (k) particle picking of SP-FCM; (l) particle picking of SP-FCM on an extremely low-SNR cryo-EM image.