Table 1.
Patient´s demographics and clinical characteristics.
| Characteristics | EC Value (n, %) | IC Value (n, %) | p Value | |||
|---|---|---|---|---|---|---|
| Age (median, range) | 66 (38, 92) | 67 (41, 94) | 0.320 | |||
| Gender | Male | 71 (60.7) | 77 (62.6) | 0.760 | ||
| Female | 46 (39.3) | 46 (37.4) | ||||
| Performance status | 0 | 42 (35.9) | 61 (49.6) | 0.055 | ||
| 1 | 53 (45.3) | 38 (30.9) | ||||
| 2 | 16 (13.7) | 13 (10.6) | ||||
| 3 | 6 (5.1) | 11 (8.9) | ||||
| Smoking status | Smoker/Former Smoker | 74 (63.2) | 82 (66.7) | 0.579 | ||
| Never smoker | 43 (36.8) | 41 (33.3) | ||||
| Disease stage | III (A/B/C) | 22 (18.8) | 23 (18.7) | 0.984 | ||
| IV | 95 (81.2) | 100 (81.3) | ||||
| Histology | Adenocarcinoma | 116 (99.1) | 123 (100) | 0.304 | ||
| Adenosquamous | 1 (0.9) | 0 | ||||
| TTF1 IHQ | Positive | 101 (86.3) | 100 (81.3) | 0.070 | ||
| Negative | 5 (4.3) | 15 (12.2) | ||||
| Unknown | 11 (9.4) | 8 (6.5) | ||||
| Specimen type | Histologic | Bronchial | 31 (26.5) | 22 (17.8) | 0.487 | |
| Lung | 51 (43.6) | 63 (51.2) | ||||
| Pleura | 10 (8.5) | 7 (5.7) | ||||
| Brain | 2 (1.7) | 5 (4.1) | ||||
| Bone | 2 (1.7) | 1 (0.8) | ||||
| Liver | 0 | 2 (1.6) | ||||
| Lymph node | 0 | 3 (2.4) | ||||
| Skin | 0 | 1 (0.8) | ||||
| Small bowel | 0 | 1 (0.8) | ||||
| Total | 96 (82.1) | 105 (85.4) | ||||
| Cytologic | Lung-FNA | 2 (1.7) | 0 | |||
| EBUS-FNA | 2 (1.7) | 2 (1.6) | ||||
| Pleural fluid | 12 (10.2) | 10 (8.1) | ||||
| Pericardial fluid | 1 (0.9) | 0 | ||||
| Bronchial washing or brushing | 0 | 4 (3.2) | ||||
| Lymph node | 4 (3.4) | 2 (1.6) | ||||
| Total | 21 (17.9) | 18 (14.6) | ||||
| Molecular status (Standard approach) | EGFR | Mutated | 22 (18.8) | |||
| ALK | EML4-ALK | 9 (7.7) | ||||
| UC | 86 (73.5) | |||||
| Total | 117 (100) | |||||
FNA, Fine-needle aspiration; UC, unclassifiable.