Table 2.
Eight Potential Beneficial Effects of MSCs in Kidney Transplantation | |||
---|---|---|---|
I. | Angiogenesis/arteriogenesis [25,38] | V. | Increase in T regulatory cells [16] |
II. | Decreased fibrosis [39,52,53] | VI. | Inhibition of cytotoxic T cell proliferation [15] |
III. | Decreased inflammation [39,40,51] | VII. | Less tissue damage (lower LDA and MDA) [50] |
IV. | Improved function of glomeruli and tubuli [52] | VIII. | Upregulation of genes encoding proteins involved in improved membrane transport of ions [50] |