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. 2019 Aug 21;11(9):1222. doi: 10.3390/cancers11091222

Figure 1.

Figure 1

(A) Heatmap of serum metabolites including glucose, glycerol, amino acids, organic acids and ketones, amine, and acylcarnitines from mice treated with vehicle, Folfiri (Fol), ACVR2B/Fc, (ACVR), and the combination Folfiri plus ACVR2B/Fc (Fol.ACVR). Only metabolites that demonstrated at least one significant intergroup difference as evaluated by one-way ANOVA with Tukey’s multiple testing correction and p-value less than 0.05 are shown. (B) Heatmap of lipids including lysophospholipids (lysoPCs), glycerophospholipids (PCs), and sphingomyelins. A total of 130 metabolites are shown as z-scores in the heatmaps.