Figure 8.

The effect of P1G10 on mediators of oxidative stress in UVB-irradiated skin. Mice were exposed to UVB (2.4 J cm⁻¹) and treated with Natrosol gel (vehicle) or 0.1% and 1% P1G10. After 24 h, the skin of euthanized animals was dissected and processed for analysis. (A) Antioxidant activity measured by DPPH assay. (B) Content of malondialdehyde (MDA); (C) production of dichlorofluorescein (DCF). For details see the Materials and Methods. Data are expressed as mean ± SEM of 6–8 animals per group (* p < 0.05, ** p < 0.01, *** p < 0.001 differences versus Vehicle, ANOVA, Newman–Keuls post-test).