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. 2019 Sep 4;8(9):1028. doi: 10.3390/cells8091028

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Comparison of the severity of ischemic strokes induced by d-MCAO and c-MCAO. Wild-type (WT) hamsters were subjected to d-MCAO and c-MCAO for 24 h.(A) Representative images of six coronal brain sections stained with 2, 3, 5-triphenyltetrazolium chloride (TTC) staining. (B) Quantification of the infarct volumes in Sham, d-MCAO, and c-MCAO from (A) (n = 6/group). (C) Measurement of cerebral blood flow after ischemia by laser Doppler transducer (n = 6–8/group). (D) Time course analysis of infarct volume in ischemic hamsters induced by d-MCAO and c-MCAO (n = 6–8/group). (E) Representative images of the Evan’s blue (EB)-stained whole brains in sham, d-MCAO, and c-MCAO group. (F) Quantification of the Evan’s blue extravasation; data are expressed as mean ± SD. * p < 0.05; ** p < 0.01 versus sham group.