Table 1.
Allele numbers of MHC genes in human and cynomolgus macaque.
| Region | Allele Group | HLA Locus | Allele Num. | Mafa Locus | Allele Num. |
|---|---|---|---|---|---|
| Class I | MHC-F | HLA-F | 44 | Mafa-F | 8 |
| MHC-G | HLA-G | 68 | Mafa-G | 10 | |
| MHC-AG | X | X | Mafa-AG | 36 | |
| MHC-A | HLA-A | 5,018 | Mafa-A1 | 320 | |
| Mafa-A2 | 83 | ||||
| Mafa-A3 | 30 | ||||
| Mafa-A4 | 38 | ||||
| Mafa-A5 | 8 | ||||
| Mafa-A6 | 14 | ||||
| Mafa-A8 | 1 | ||||
| MHC-E | HLA-E | 30 | Mafa-E | 16 | |
| MHC-C | HLA-C | 4,852 | X | X | |
| MHC-B | HLA-B | 6,096 | Mafa-B | 717 | |
| Mafa-B11L | 5 | ||||
| Mafa-B16 | 11 | ||||
| Mafa-B17 | 4 | ||||
| Mafa-B20 | 2 | ||||
| Mafa-B21 | 2 | ||||
| MHC-I | X | X | Mafa-I | 76 | |
| Class II | MHC-DR | HLA-DRA | 7 | Mafa-DRA | 52 |
| HLA-DRB1 | 2,403 | Mafa-DRB*W | 160 | ||
| HLA-DRB3 | 217 | Mafa-DRB1 | 82 | ||
| HLA-DRB4 | 108 | Mafa-DRB3 | 13 | ||
| HLA-DRB5 | 77 | Mafa-DRB4 | 10 | ||
| Mafa-DRB5 | 18 | ||||
| Mafa-DRB6 | 35 | ||||
| MHC-DQ | HLA-DQA1 | 149 | Mafa-DQA1 | 100 | |
| HLA-DQB1 | 1,560 | Mafa-DQB1 | 107 | ||
| MHC-DO | HLA-DOA | 12 | Mafa-DOA | 15 | |
| HLA-DOB | 13 | Mafa-DOB | 16 | ||
| MHC-DM | HLA-DMA | 7 | Mafa-DMA | 11 | |
| HLA-DMB | 13 | Mafa-DMB | 7 | ||
| MHC-DP | HLA-DPA1 | 106 | Mafa-DPA1 | 91 | |
| HLA-DPB1 | 1,360 | Mafa-DPB1 | 98 | ||
| Total | 22,140 | 2196 |
The HLA and Mafa MHC allele numbers refer to IPD-IMGT/HLA Release 3.36.0 and IPD-MHC Release 3.2.0.0 (2018-12-18) build 780, respectively.