Table 1.
Socio-demographic, anthropometric measures and metabolic profile of 200 adult females with obesity included in the study.
| Parameters | Mean ± SD |
|---|---|
| Age (years) | 36.98 ± 11.10 |
| BMI (kg/m2) | 45.19 ± 6.30 |
| Grade II obesity | 41, 20.5% |
| Grade III obesity | 159, 79.5% |
| Waist circumference (cm) | 126.74 ± 17.05 |
| SBP (mmHg) | 126.89±15.29 |
| DBP (mmHg) | 80.68 ± 10.84 |
| GH peak response (µg/L) | 3.72 ± 4.29 |
| GH deficit 1 | 123, 61.5% |
| IGF-1 (µg/L) | 151.93 ± 64.93 |
| IGF-1 (SDS) | −2.43 ± 1.85 |
| IGF-1(SDS) deficiency 2 | 142, 71.0% |
| Fasting glucose (mg/dL) | 105.27 ± 36.79 |
| Fasting insulin (µU/mL) | 19.95 ± 11.76 |
| Total cholesterol (mg/dL) | 187.36 ± 47.88 |
| HDL cholesterol (mg/dL) | 50.17 ± 11.94 |
| LDL cholesterol (mg/dL) | 106.54 ± 49.96 |
| Fasting triglycerides (mg/mL) | 151.95 ± 53.10 |
| AST (U/L) | 30.15 ± 16.44 |
| ALT (U/L) | 41.70 ± 30.21 |
| γGT (U/L) | 41.37 ± 25.38 |
| CRP (ng/mL) | 2.33 ± 1.01 |
| HoMA-IR | 6.04 ± 6.55 |
| >Cut-off | 155, 77.5% |
| VAI | 1.86 ± 0.94 |
| >Cut-off | 57, 28.5% |
| FLI | 96.43 ± 6.79 |
| >Cut-off | 197, 98.5% |
| Metabolic syndrome (presence) | 88, 44.0% |
1 GH (growth hormone) peak response after GHRH (GH releasing hormone) + ARG (arginine hydrochloride) was classified as deficient (GH deficit 1) when GH peak was ≤4.2 mg/L. 2 IGF-1 levels were classified as deficient (IGF-1 (insulin-like growth factor I) deficiency 2) when the SDS from the mean was <−2 for age and gender.