Figure 1.

Lycopene inhibits cell proliferation and increases DNA fragmentation. (A) The cells were treated with the indicated concentrations of lycopene for 24 and 48 h. Cell viability was assessed using the trypan blue exclusion test. (B) The cells were treated with the indicated concentrations of lycopene for 24 h. DNA fragmentation was assessed by the amount of nucleosome-bound DNA in the cell lysates. The level of DNA fragmentation for untreated cells was set as 1. * p < 0.05 versus the cells treated with a vehicle tetrahydrofuran without lycopene (“none”).