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. 2019 Aug 27;11(9):2014. doi: 10.3390/nu11092014

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Creatine maternal supplementation affects input resistance in adult CA1 neurons. Neurons of treated rats excited by current injections above 150 pA do not show differences in input resistance compared to treated neurons excited by current injections below 150 pA, while such differences were found in neurons of control rats. Two-way ANOVA with Intensity of stimulation and Treatment (CTRL vs TREAT) as independent variables while the litter was considered as a blocking factor; Intensity: F (1, 42) = 14.69 p = 0.0004; >150 pA CTRL: n=11 neurons; TREAT: n = 11 neurons; <150 pA CTRL: n = 14 neurons; TREAT: n = 11 neurons. Sidak’s multiple comparisons test: <150 pA CTRL vs. >150 pA CTRL * p = 0.0116. CTRL = 5 rats; TREAT = 5 rats.